{"id":2752,"date":"2026-05-29T12:42:48","date_gmt":"2026-05-29T11:42:48","guid":{"rendered":"https:\/\/breakingnews.drinkfood.info\/?p=2752"},"modified":"2026-05-29T12:42:48","modified_gmt":"2026-05-29T11:42:48","slug":"disaster-in-san-francisco-49ers-injury-woes-explode-again-with-alarming-update-on-key-running-back-the-setback-that-threatens-to-derail-another-season","status":"publish","type":"post","link":"https:\/\/breakingnews.drinkfood.info\/?p=2752","title":{"rendered":"DISASTER IN SAN FRANCISCO: 49ers Injury Woes Explode Again With Alarming Update on Key Running Back \u2014 The Setback That Threatens to Derail Another Season"},"content":{"rendered":"<p><img decoding=\"async\" src=\"https:\/\/heavy.com\/wp-content\/uploads\/2026\/05\/Isaac-Guerendo-e1780004981148.jpg?quality=65&amp;strip=all&amp;w=780\" \/><\/p>\n<p>The story of the San Francisco 49ers\u2018 2025 campaign was injuries, which just so happens to be what the story of the 2024 season was, too. Whereas the 2024 team succumbed to its injuries, last year\u2019s squad managed to overcome its injury woes to make a run all the way to the divisional round of the playoffs.<\/p>\n<p>Simply put, San Fran is hoping to stay relatively healthy in 2026 because if it can, it has a legitimate shot at making a Super Bowl run. Fans of the team are going to want to shield their eyes, though, because head coach Kyle Shanahan recently revealed that running back Isaac Guerendo suffered a serious injury, even though the team isn\u2019t even playing games currently.<\/p>\n<p>Isaac Guerendo Recovering from Torn Pectoral Muscle<\/p>\n<blockquote class=\"twitter-tweet\" data-width=\"550\" data-dnt=\"true\">\n<p lang=\"en\" dir=\"ltr\"><a href=\"https:\/\/x.com\/hashtag\/49ers?src=hash&amp;ref_src=twsrc%5Etfw\">#49ers<\/a> HC Kyle Shanahan said RB Isaac Guerendo tore his pectoral while lifting weights and he\u2019s expected to be out until late in training camp. <a href=\"https:\/\/t.co\/hXWA3oFn7V\">pic.twitter.com\/hXWA3oFn7V<\/a><\/p>\n<p>&mdash; Ari Meirov (@MySportsUpdate) <a href=\"https:\/\/x.com\/MySportsUpdate\/status\/2060110824039973218?ref_src=twsrc%5Etfw\">May 28, 2026<\/a><\/p><\/blockquote>\n<p><script async src=\"https:\/\/platform.x.com\/widgets.js\" charset=\"utf-8\"><\/script><\/p>\n<p>A fourth-round pick in the 2024 NFL Draft, Guerendo was one of the lone bright spots for the team as a rookie. With both Christian McCaffrey and Jordan Mason battling injuries, that thrust Guerendo into action sooner than expected, but he managed to flash his potential whenever he found his way onto the field (84 CAR, 420 YDS, 4 TD, 15 REC, 152 YDS).<\/p>\n<p>While Mason departed for the Minnesota Vikings last offseason, McCaffrey was fully healthy for the 2025 campaign, and the team picked up Brian Robinson Jr. in a trade with the Washington Commanders, which put Guerendo back in the No. 3 spot on the depth chart. While he was active for 14 games, Guerendo didn\u2019t log a single statistic of note last year on the offensive side of the ball.<\/p>\n<p>Heading into the new season, though, Guerendo appeared to have a real shot at earning the No. 2 gig behind McCaffrey, as Robinson signed with the Atlanta Falcons in free agency. However, Shanahan recently revealed that Guerendo suffered a torn pectoral muscle in April, which will keep him on the sidelines until late in training camp.<\/p>\n<p>\u201c49ers HC Kyle Shanahan said RB Isaac Guerendo tore his pectoral while lifting weights and he\u2019s expected to be out until late in training camp,\u201d Ari Meirov of The 33rd Team shared in a post on X.<\/p>\n<p><strong>49ers Won\u2019t Love This Isaac Guerendo Injury Update<\/strong><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/heavy.com\/wp-content\/uploads\/2024\/12\/GettyImages-2188927366-1.jpg?quality=65&amp;strip=all&amp;w=782\" \/><\/p>\n<p>The silver lining here is that Guerendo still could be ready to go for the start of the season. Considering how many injuries this team has dealt with in recent years, though, this just isn\u2019t the sort of news anyone in San Francisco wants to hear. Guerendo has battled his fair share of ailments to begin his career, too, so from an individual perspective, this is another tough blow for him.<\/p>\n<p>With Guerendo out, Jordan Jones and third-round rookie Kaelon Black will spend much of the summer battling it out for the backup job behind McCaffrey. Guerendo has more NFL experience than either of those guys, but the time he\u2019s being forced to spend recovering from this injury is going to put him at a disadvantage. Guerendo could still earn the No. 2 spot on the running back depth chart, but this position has suddenly become much more intriguing in the blink of an eye.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The story of the San Francisco 49ers\u2018 2025 campaign was injuries, which just so happens to be what the story of the 2024 season was, too. Whereas&#8230; <\/p>\n","protected":false},"author":2,"featured_media":2753,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-2752","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-nfl"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>DISASTER IN SAN FRANCISCO: 49ers Injury Woes Explode Again With Alarming Update on Key Running Back \u2014 The Setback That Threatens to Derail Another Season - Sports USA<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/breakingnews.drinkfood.info\/?p=2752\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"DISASTER IN SAN FRANCISCO: 49ers Injury Woes Explode Again With Alarming Update on Key Running Back \u2014 The Setback That Threatens to Derail Another Season - Sports USA\" \/>\n<meta property=\"og:description\" content=\"The story of the San Francisco 49ers\u2018 2025 campaign was injuries, which just so happens to be what the story of the 2024 season was, too. 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